Linaclotide
keywords
- Linaclotide Base
- maxime parabilis pretium
- # 851199-59-2 CAS
Details Velox
- ProName: Linaclotide
- CASNo: 851199-59-2
- Molecular Formula: C59H79N15O21S6
- Species: album pulveris
- Application: propter constipationem sanantes
- DeliveryTime: promptum sit amet
- Sarcina: secundum mos est scriptor requisitis
- Portus: Shenzhen
- ProductionCapacity: Kilogram I / mense
- Quod puritas, XCVIII%
- Repono: II ℃ ~ VIII. protected de lumine
- Translationem, ab aeris
- LimitNum: I Gram
superiority
details
Product: Linaclotide
Synonym: Linaclotide Acetate
CAS No: 851199-59-2
Molecular Formula: C59H79N15O21S6
Molecular Weight: 1526,8
Species: Alba pulveris
puritas:> XCVIII%
Sequentia NH2, Cys, Cys-Glu-fini-Cys, Cys ASN, -Pro, Alaricus, Cys, Thr, rivale, Cys fini-O-
Linaclotide est Synthetica, et quattuor amino acidum precursor agonist intestinorum guanylate cyclase genus C (GC, C), quae est familiae structuram related to the guanylin precursor cum secretagogue, analgesic et alvum activities. In oris administrationem, suaque vi movet linaclotide alligat ad C G. C, sita in receptores, luminal intestinorum superficiem epithelium. Cyclica guanosine monophosphate Cocci augetur retrahitur (cGMP) quod ex guanosine triphosphate (T). cGMP operatur cystic fibrosis transmembrane Conductancia ordinator (CFTR) et movet secretionem in intestinorum chloride bicarbonate et lumen. Hoc promovet sodium excretion, et in lumine results in intestinorum fluidum auctus secretionem debitam. Hoc ultimately accelerat GI transit intestinorum contenta in eodem improves alvum motus et ne constipation vel mala tollit. Extracellular cGMP levels auctus ut exercent etiam antinociceptive effectum est, per quod tamen ut non amplius elucidabuntur mechanism, et ut modulamen involvere nociceptors colonic efferent dolorem inveni in fibris. GI, minime ex Linaclotide totus tractus.
