Linaclotide

  • Khoom npe: Linaclotide
  • Cas Tsis: 851199-59-2
  • Molecular Formula: C59H79N15O21S6
  • Molecular yuag: 1526,8 g / mol
  • Ib theem zuj zus: NH2-Cys-Cys-Glu-Tyr-Cys-Cys-Nug-Pro-ALA-Cys-THR-Gly-Cys-Tyr-OH
  • Tsos: Dawb hmoov
  • Daim ntawv: Siv los tua cov chim siab plob tsis so tswj syndrome nrog cem quav thiab mob cem quav uas tsis muaj lub npe hu ua
  • Pob: Raws li cov neeg uas yuav tsum tau
  • khoom Nthuav dav

    khoom cim npe

    keywords

    • Linaclotide Base
    • feem ntau pheej yig tus nqi
    • CAS # 851199-59-2

    ceev Paub meej

    • ProName: Linaclotide
    • CasNo: 851199-59-2
    • Molecular Formula: C59H79N15O21S6
    • Tsos: dawb hmoov
    • Daim ntawv: siv rau Tua cem quav
    • DeliveryTime: pab zaub mov xa tuaj
    • Pob: raws li tus neeg muas zaub uas yuav tsum tau
    • Chaw nres nkoj: Shenzhen
    • ProductionCapacity: 1 kilogram / rau lub Hlis
    • Purity: 98%
    • Cia: 2 ~ 8 ℃. kev tiv thaiv los ntawm lub teeb
    • Tsheb thauj mus los: los ntawm huab cua
    • LimitNum: 1 gram

    superiority

     

    kev peptide chaw tsim tshuaj paus nyob rau hauv Tuam Tshoj.
    zoo nrog GMP qib
    loj scale nrog sis tw nqi
    peb cov khoom muaj xws li: generic tej peptide APIs, kom hniav zoo nkauj peptide, kev cai peptides thiab kho tsiaj peptides.

     

    Paub meej

     

    Khoom: Linaclotide
    yaj: Linaclotide acetate
    CAS No.: 851199-59-2
    Molecular Formula: C59H79N15O21S6
    Molecular Nyhav: 1526,8
    Tsos: Dawb hmoov
    Purity:> 98%
    lawv liag: NH2-Cys-Cys-Glu-Tyr-Cys-Cys-Nug -Pro-ALA-Cys-THR-Gly-Cys-Tyr-OH

    Linaclotide yog ib tug hluavtaws, kaum plaub amino acid peptide thiab agonist ntawm plab hnyuv guanylate cyclase hom C (GC-C), uas yog structurally txog lub guanylin peptide tsev neeg, nrog secretagogue, analgesic thiab laxative kev ua ub no. Thaum qhov ncauj cov thawj coj, linaclotide uake mus thiab activates GC-C receptors nyob rau lub luminal nto ntawm lub plab hnyuv epithelium. Qhov no yuav tsub lub concentration ntawm intracellular cyclic guanosine monophosphate (cGMP), uas yog derived ntawm guanosine triphosphate (GTP). cGMP activates cystic fibrosis transmembrane conductance regulator (CFTR) thiab nkoos lub tso pa tawm ntawm chloride thiab bicarbonate mus rau hauv lub plab hnyuv lumen. Qhov no yeej txhawb sodium feem mus rau hauv lub lumen thiab tau nyob rau hauv ntau zog plab hnyuv kua secretion. Qhov no thaum kawg accelerates GI transit ntawm plab hnyuv txheem, pab txoj kev plob tsis so tswj zog thiab relieves cem quav. Nce extracellular cGMP theem kuj pheev ib antinociceptive nyhuv, los ntawm ib tug li ntawm tsis tau tsis siab elucidated mechanism, uas tej zaum yuav koom nrog tes taws los piav ntawm nociceptors nyob rau colonic afferent mob fibers. Linaclotide yog tsawg kawg absorbed los ntawm lub GI ib ntsuj av.

    Tuam txhab Profile:
    lub tuam txhab lub npe: Shenzhen JYMed Technology Co., Ltd.
    Xyoo Tsim: 2009
    Peev: 89,5 lab RMB
    Main khoom: oxytocin acetate, Vasopressin acetate, Desmopressin acetate, Terlipressin acetate, Caspofungin acetate, Micafungin sodium, Eptifibatide acetate, Bivalirudin TFA, Deslorelin acetate, Glucagon acetate, Histrelin acetate, Liraglutide acetate, Linaclotide Aceteate, Degarelix acetate, Buserelin acetate, Cetrorelix acetate , Goserelin
    Acetate, Argireline acetate, Metrixyl acetate, Snap-8, ... ..
    Peb siv zog rau cov tseem nrhav nyob rau hauv tshiab peptide synthesis technology thiab cov txheej txheem optimization, thiab peb kev pab neeg muaj tshaj xyoo caum ntawm kev nyob rau hauv peptide synthesis.JYM tau ntse xa ntau
    ntawm ANDA peptide APIs thiab formulated cov khoom uas muaj CFDA thiab muaj ntau tshaj plaub caug patents pom zoo.
    Peb peptide cog nyob rau hauv Nanjing, Jiangsu xeev thiab nws tau teem ib lub chaw ntawm 30,000 square meters nyob rau hauv kev ua raws cai nrog cGMP yeej. Cov kev siv thiab lub tsev raug audited thiab ntsuam xyuas los ntawm ob qho tib si domestic thiab thoob ntiaj teb neeg.
    Nrog nws zoo heev zoo, feem ntau cov kev sib tw cov nqi thiab muaj zog kev them nyiaj yug, JYM tsis tsuas tau tau qhuas txog rau nws cov khoom los ntawm kev tshawb fawb cov koom haum thiab chaw ua tshuaj industries, tab sis kuj ua ib qho ntawm feem txhim khu kev qha lwm tus neeg uas peptides nyob rau hauv Tuam Tshoj ,. JYM yog nplooj siab mus yuav ib tug ntawm lub ntiaj teb no tus leading peptide mob nyob rau hauv lub nyob ze yav tom ntej.

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