Desmopressin acetate ukuba isitofu

1ml: 4μg / 1ml: Amandla 15μg

olubonisa:

Zikhombisa AND SOKUSETYENZISWA

Kubazali bakhe A: Desmopress in acetate Inaliti 4 mcg / ml kuboniswe izigulana kubazali bakhe A kunye namaqondo factor VIII umsebenzi coagulant omkhulu kwe-5%.

Desmopress in Inaliti acetate kuya ukugcina hemostasis kwizigulane kunye kubazali bakhe A ngexesha iinkqubo zotyando kunye postoperatively xa kubhalwa kwimizuzu engama-30 phambi kokuba inkqubo ecwangcisiweyo.

Desmopress in Inaliti acetate baya kuyeka ukopha kubazali bakhe izigulane A kunye iziqephu yokwenzakala ezizenzekelayo okanye umothuko-kwezi- ezifana hemarthroses, hematomas intramuscular okanye mucosal ukopha.

Desmopress in Inaliti acetate akukho eboniswe yonyango kubazali bakhe A kunye factor VIII amanqanaba umsebenzi coagulant esilingana okanye ngaphantsi kwe-5%, okanye ngenxa yonyango kubazali bakhe B, okanye izigulane abo factor VIII izilwa-buhlungu.

Kwiimeko ezithile lwezonyango, ukuze ugwetyelwe ukuzama desmopress kwi isitofu acetate kwizigulane kunye factor VIII amanqanaba phakathi kwe-2% ukuya kwi-5%; Noko ke, le izigulane kufuneka esweni ngenyameko. Disease von Willebrand kaThixo (Uhlobo I): Desmopres s kwi acetate isitofu 4 mcg / ml kuboniswe ukuba izigulane abangeva ukumodareyitha isifo classic von Willebrand kaThixo (Uhlobo I) kunye factor izinga VIII mkhulu kwe-5%. Desmopress in Inaliti acetate kuya ukugcina hemostasis kubaguli abangeva ukumodareyitha isifo von Willebrand ebudeni iinkqubo zotyando kunye postoperatively xa kubhalwa kwimizuzu engama-30 phambi kokuba inkqubo ecwangcisiweyo.

Desmopress in Inaliti acetate uya kudla uyeke ukopha ngobulali ukumodareyitha izigulane von Willebrand kunye iziqephu yokwenzakala ezizenzekelayo okanye umothuko-kwezi- ezifana hemarthroses, hematomas intramuscular okanye mucosal ukopha.

izigulane isifo Abo von Willebrand abaye baya ubuncinane ukuphendula zezo ezinzima homozygous isifo von Willebrand kunye factor VIII umsebenzi coagulant kunye factor VIII von

amanqanaba Willebrand factor iantigens ngaphantsi kwe-1%. Ezinye izigulane kusabela ngendlela variable ngokuxhomekeke kuhlobo isiphako ezinto abanazo. Ukopha ixesha umsebenzi coagulant factor VIII, ristocetin umsebenzi cofactor, kunye von Willebrand factor iantigens kufuneka zihlolwe ngethuba lolawulo desmopress kwi naliti acetate ukuqinisekisa ukuba amazinga afanelekileyo lungafezekiseka.

Desmopress in Inaliti acetate akukho kuboniswe ukuba unyango lwesifo kakhulu Classic von Willebrand kaThixo (Uhlobo I) kwaye xa kukho ubungqina wefom engaqhelekanga ngemolekyula of factor VIII iantigens.

Diabetes Insipidus: Desmopress e acetate isitofu 4 mcg / ml eziboniswe njengezehlelo therapy replacement antidiuretic kulawulo central (cranial) seswekile insipidus kunye nolawulo polyuria okwethutyana kunye polydipsia ilandelayo trauma intloko okanye uqhaqho kummandla yebhinqa.

Desmopress in Inaliti acetate ke bazibone ukuba unyango nephrogenic seswekile insipidus.

Desmopress in acetate kwakhona njengento ukulungiselela intranasal. Nangona kunjalo, le ndlela of delivery unako sengozini ngenxa ezahlukeneyo izinto ezinokwenza insufflation ngeempumlo kuphumelele okanye engafanelekanga.

Ezi ziquka abahluphekayo intranasal edalwayo, ukuxinana ngeempumlo kunye ukuvaleka, ukubhobhoza ngeempumlo, yoma of ngeempumlo isifo, nokuthimliswa kakhulu atrophic. ukunikezelwa Intranasal ingahle ingalungile apho kukho umgangatho othile lokuqonda. Ukongeza, iinkqubo cranial zotyando, ezifana transsphenoidal hypophysectomy, ukudala iimeko apho enye indlela wolawulo iyafuneka njengokuba kwiimeko ngeempumlo nokupakisha okanye angalulama uqhaqho.

Izimo

Desmopress in acetate isitofu 4 mcg / ml contraindicated xa abantu hypersensitivity eyaziwa ukuba desmopress kwi acetate okanye naziphi na iinxalenye desmopress in acetate isitofu 4 mcg / ml.

Desmopress in Inaliti acetate yi contraindicated kwizigulane kunye olungephi ukuya ongaboniyo kakhulu sezintso (ichazwa njenge sokucoceka creatinine ngezantsi 50ml / min).

Desmopress in Inaliti acetate yi contraindicated kwizigulane kunye hyponatremia okanye imbali hyponatremia.