Desmopressin nthochi jekeseni

1ml: 4μg / 1ml: 15μg Mphamvu

chosonyeza:

Zikuonetsa NDI zakagwiritsidwe

Amapatsira mwana wake A: Desmopress mu nthochi jekeseni 4 mcg / mL akusonyeza odwala ndi amapatsira mwana wake A ndi milingo chinthu VIII coagulant ntchito zazikulu kuposa 5%.

Desmopress mu jekeseni nthochi zambiri kukhala hemostasis odwala ndi amapatsira mwana wake A pa popanga munthu opaleshoni ndipo postoperatively pamene kutumikiridwa mphindi 30 asanayambe ndondomeko uchitike.

Desmopress mu jekeseni nthochi nawonso magazi asiye kutuluka mu amapatsira mwana wake odwala A ndi nkhani za kuvulala mowiriza mofuna kapena kupwetekedwa mtima chifukwa chovutika monga hemarthroses, hematomas mu mnofu kapena mucosal magazi.

Desmopress mu jekeseni nthochi si anasonyeza zochizira amapatsira mwana wake A ndi chinthu VIII milingo coagulant ntchito wofanana kapena zochepa 5% kapena zochizira amapatsira mwana wake B, kapena odwala amene ali chinthu VIII chitetezo.

Pa mavuto ena ovutika mwina wolungama kuyesa desmopress mu jekeseni nthochi odwala ndi chinthu milingo VIII pakati pa 2% 5%; Komabe, odwalawo ayenera kuyang'aniridwa. Von Willebrand Nthenda (Type I): Desmopres m mu nthochi jekeseni 4 mcg / mL akusonyeza odwala ndi wofatsa chowongolera matenda tingachipeze powerenga Von Willebrand a (Type I) ndi chinthu VIII milingo kuposa 5%. Desmopress mu jekeseni nthochi zambiri kukhala hemostasis odwala ndi wofatsa chowongolera matenda Von Willebrand mkati popanga munthu opaleshoni ndipo postoperatively pamene kutumikiridwa mphindi 30 asanayambe ndondomeko uchitike.

Desmopress mu jekeseni nthochi kaŵirikaŵiri magazi asiye kutuluka mu wofatsa chowongolera odwala Von Willebrand ndi nkhani za kuvulala mowiriza mofuna kapena kupwetekedwa mtima chifukwa chovutika monga hemarthroses, hematomas mu mnofu kapena mucosal magazi.

matenda amene Von Willebrand a odwala amene wochepetsetsa akulabadira anthu aakulu homozygous matenda Von Willebrand ndi chinthu VIII coagulant ntchito ndi chinthu VIII Von

misinkhu Willebrand chinthu Antigen zosakwana 1%. Odwala ena akhoza kumvetsera mwa kachitidwe variable malingana ndi mtundu wa chilema maselo ali. Magazi nthawi ndi chinthu VIII coagulant ntchito, ristocetin ntchito cofactor, ndi Von Willebrand chinthu Antigen zifunike pa makonzedwe a desmopress mu jekeseni nthochi kuonetsetsa kuti mulingo okwanira zakhalapo.

Desmopress mu jekeseni nthochi si anasonyeza zochizira matenda aakulu tingachipeze powerenga Von Willebrand a (Type I) ndi pamene pali umboni wa nthenda maselo mtundu wa chinthu VIII Antigen.

Shuga Insipidus: Desmopress mu nthochi jekeseni 4 mcg / mL akusonyeza kuti m'malo mankhwala antidiuretic pa kayendetsedwe chapakati (cranial) shuga insipidus ndi kasamalidwe wa polyuria kanthawi polydipsia zotsatirazi zoopsa mutu kapena opaleshoni m'dera pituitary.

Desmopress mu jekeseni nthochi ndi operewera zochizira nephrogenic shuga insipidus.

Desmopress mu nthochi likupezeka ngati kukonzekera intranasal. Komabe, njira imeneyi ya kubala akhoza kusweka mwa zosiyanasiyana zinthu zimene zingachititse insufflation m'mphuno osamveka kapena zosayenera.

Zikuphatikizapo osauka intranasal mayamwidwe, kuchulukana m'mphuno ndipo blockage, kumaliseche m'mphuno, manja a amphuno mucosa, ndi woopsa atrophic rhinitis. Intranasal yobereka kungakhale zosayenera kumene msinkhu mkhutu cha chikumbumtima. Komanso, cranial popanga munthu opaleshoni, monga transsphenoidal hypophysectomy, kulenga zinthu kumene Njira ina ya utsogoleli chofunika monga milandu m'mphuno kulongedza katundu kapena kuchira opaleshoni.

contraindications

Desmopress mu nthochi jekeseni 4 mcg / mL ali contraindicated mu anthu ndi odziwika hypersensitivity kuti desmopress mu nthochi kapena kuti aliyense wa zigawo zikuluzikulu za desmopress mu nthochi jekeseni 4 mcg / mL.

Desmopress mu jekeseni nthochi ndi contraindicated odwala ndi zolimbitsa kuti kuwonongeka aakulu aimpso (limanenedwa ngati chilolezo creatinine pansipa 50ml / Mph).

Desmopress mu jekeseni nthochi ndi contraindicated odwala ndi hyponatremia kapena mbiri ya hyponatremia.