Fọọmu Molecular:

C76H104N18O19S2

Ibi Molecular ibatan:

1637,90 g / mol

Nọmba CAS:

38916-34-6 (net)

Ibi ipamọ igba pipẹ:

-20 ± 5°C

Awọn itumọ ọrọ sisọ:

Somatostatin-14; SRIF-14;
Somatotropin Itusilẹ-Idinamọ ifosiwewe; SRIF

Ilana:

H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH acetate iyọ (Disulfide bond)

Awọn aaye Ohun elo:

Ẹjẹ ọgbẹ
Gastritis hemorrhagic
Lẹhin ti iṣẹ abẹ pancreatic ati duodenal fistulae
Ẹjẹ ẹjẹ ti o yatọ

Ohun Nṣiṣẹ:

Somatostatin (SRIF) jẹ inhibitor ti itusilẹ homonu idagba lati inu pituitary iwaju ati nitorinaa antagonist ti GRF.Somatostatin npa itusilẹ ti ọpọlọpọ awọn homonu miiran ti o ni ipa ninu ilana awọn iṣẹ iṣe-ara pataki ti iṣan-ara inu ikun. Somatostatin tun ṣe idiwọ iṣelọpọ TSH.Somatostatin jẹ peptide 14-amino acid ti a npè ni fun agbara rẹ lati dẹkun itusilẹ GROWTH HORMONE pituitary, ti a tun pe ni ifasilẹ ifasilẹ somatotropin. O ṣe afihan ni aarin ati awọn eto aifọkanbalẹ agbeegbe, ikun, ati awọn ara miiran. SRIF tun le ṣe idiwọ itusilẹ ti HORMONE-SIMULATING THYROID; PROLACTIN; INSULIN; ati GLUCAGON lẹgbẹẹ ṣiṣe bi neurotransmitter ati neuromodulator. Ni nọmba awọn eya pẹlu eniyan, afikun fọọmu ti somatostatin wa, SRIF-28 pẹlu itẹsiwaju 14-amino acid ni N-terminal.

Ifihan ile ibi ise: