Somatostatin

Limolek'hule Mokgwa wa ho Nahana:

Setšoantšo sa C76H104N18O19S2

A lekanyelitsoeng limolek'hule Misa:

1637,90 g, / Mol

CAS-Number:

38916-34-6 (letlooeng)

Nako e telele Storage:

-20 ± 5 ° C

synonymes:

Somatostatin-14; SRIF-14;
Somatotropin Release-Inhibiting Ntlha; SRIF

tatelano:

H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-rakir-Phe-rakir-ditshebeletso-Cys-OH ea acetate letsoai (Disulfide tlamo e)

Masimong a Kopo:

Seso tsoa mali
Hemorrhagic gastritis
Postoperative pancreatic le duodenal fistulae
Variceal hemorrhage

Active ntho:

Somatostatin (SRIF) ke sesitisa ya kgolo hormona ho lokolloa le pituitary anterior 'me ka hona e antagonist tsa GRF.Somatostatin patelang batho ho lokolloa ha mefuta e fapaneng ya li-hormone tse ling tse amehang ka molao oa tsamaiso ea mesebetsi bohlokoa fisioloji pampitšaneng ena gastrointestinal. Somatostatin hape thibela TSH production.Somatostatin ke 14-amino acid e peptide bitsoang bakeng sa matla a ho thibela metsoako pituitary KHŌLO Hormone lokolloa, eo hape a bitsoang somatotropin lokolloe-inhibiting lebaka. E bontšoa ka bohareng le ka pheriferale tsamaiso ea methapo ea kutlo, e ntse likahare ka le litho tsa ka hare tse ling. SRIF ka boela thibela metsoako lokolloa ha thyroid-Stimulating Hormone; PROLACTIN; ka insulin; le GLUCAGON ntle ho itšoara joaloka e neurotransmitter le neuromodulator. A 'maloa a mefuta e ho akarelletsa le batho ba, ho na le mofuta o eketsehileng oa somatostatin, SRIF-28 le asiti katoloso 14-amino ka N-bolaeang.

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