Somatostatin

Molecular Formula:

C76H104N18O19S2

Tus kwv tij Molecular pawg:

1637,90 g / mol

CAS-Number:

38916-34-6 (net)

Long-term Cia:

-20 ± 5 ° C

txhais:

Somatostatin-14; SRIF-14;
Somatotropin Tso-inhibiting Factor; SRIF

ib theem zuj zus:

H-ALA-Gly-Cys-Lys-Nug-Phe-Phe-Trp-Lys-THR-Phe-THR-Ser-Cys-OH acetate ntsev (Disulfide daim ntawv cog lus)

Liaj teb ntawm Daim Ntawv Thov:

Rwj los ntshav
Hemorrhagic gastritis
postoperative pancreatic thiab duodenal fistulae
Variceal hemorrhage

Active Substance:

Somatostatin (SRIF) yog ib qho inhibitor ntawm kev loj hlob lawm tso tawm los ntawm lub anterior pituitary thiab chaw pib ib antagonist ntawm GRF.Somatostatin suppresses qhov kev tso tawm ntawm ib tug ntau yam ntawm lwm yam tshuaj hormones muab kev koom tes nyob rau hauv cov kev cai ntawm ib qho tseem ceeb muaj sia functions ntawm tus mob huam. Somatostatin kuj cheeb TSH production.Somatostatin yog ib tug 14-amino acid peptide lub npe tis rau nws muaj peev xwm inhibit pituitary loj lawm tso tawm, kuj hu ua somatotropin tso tawm-inhibiting tau. Nws yog qhia nyob rau hauv lub hauv paus thiab peripheral tshee systems, lub plab, thiab lwm yam kabmob. SRIF kuj inhibit qhov kev tso tawm ntawm lub qog-stimulating lawm; PROLACTIN; insulin; thiab GLUCAGON dua li kuj yog ib neurotransmitter thiab neuromodulator. Nyob rau hauv ib tug xov tooj ntawm hom xws li tib neeg, muaj ib tug ntxiv hauv daim ntawv ntawm somatostatin, SRIF-28 nrog ib tug 14-amino acid extension ntawm lub N-davhlau ya nyob twg.

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