Magaca Kiimikada:(S) -2-((2R,3R) -3- ((S) -1-((3R,4S,5S) -4-((S) -N,3-dimethyl-2-((S)-3-methyl-2-(methylamino) butanamido) butanamido) -3-methoxy-5-methylheptanoyl) pyrrolidin-2-yl) -3-methpropanami-2-3-meth-propanamide-3-meth-propanamiyl-3-methyl.

Miisaanka Molecular:731.96
Formula:C39H65N5O8
CAS#:141205-32-5
Xalka:DMSO ilaa 20mM

Waxqabadka Nafleyda
Monomethyl auristatin F (MMAF) ama desmethyl-auristatin F waa wakiilka ka hortagga-tubulin-ka ee joojiya kala-qaybinta unugyada iyada oo xannibaysa polymerization of tubulin. Waa cusubauristatin asaloo leh C-terminal phenylalanine oo lagu soo oogay taas oo hoos u dhigaysa waxqabadkeeda cytotoxic marka la barbardhigo dhiggeeda aan la dallacin, monomethyl auristatin E (MMAE). Intaa waxaa dheer, kooxda amino N-terminal waxay leeyihiin oo kaliyamidmethyl beddelka halkii laba sida inauristatin Flafteeda.