Sunan Sinadari:(S) -2- ((2R,3R) -3- ((S) -1- ((3R,4S,5S) -4- ((S) -N,3-dimethyl-2- ((S) -3-methyl-2- (methylamino) butanamido) butanamido) -3-methoxy-5-methylheptanoyl) pyrrolidin-2-yl) -3-methproxy-2-3 methyl acid

Nauyin Kwayoyin Halitta:731.96
Tsarin tsari:Saukewa: C39H65N5O8
CAS#:141205-32-5
Solubility:DMSO har zuwa 20 mM

Ayyukan Halittu
Monomethyl auristatin F (MMAF) ko desmethyl-auristatin F wakili ne na anti-tubulin wanda ke hana rarraba tantanin halitta ta hanyar toshe polymerization na tubulin. Wani sabo neauristatin na asalitare da cajin C-terminal phenylalanine wanda ke rage ayyukan cytotoxic idan aka kwatanta da takwaransa mara caji, monomethyl auristatin E (MMAE). Bugu da kari, rukunin amino N-terminal yana da kawaidayaMai maye gurbin methyl maimakon biyu kamar inAuristatin Fkanta.