-
Monomethylauristatin F (MMAF)
Orukọ Kemikali: (S) -2- ((2R,3R) -3- ((S) -1- ((3R,4S,5S) -4- ((S) -N,3-dimethyl-2- ((S) -3-methyl-2- (methylamino) butanamido) butanamido) -3-methoxy-5-methylheptanoyl) pyrrolidin-2-yl) -2-3-methprophetyl-prophe-propheyl-prophe-propheyl-propheyl-propheyl. Òṣuwọn Molecular: 731.96 Formula: C39H65N5O8 CAS#: 141205-32-5 Solubility: DMSO to 20 mM Biological Activity Monomethyl auristatin F (MMAF) tabi desmethyl-auristatin F jẹ aṣoju egboogi-tubulin ti o ṣe idiwọ pipin sẹẹli ti tubulin. O jẹ... -
Monomethyl Auristatin E (MMAE)
Orukọ Kemikali: (S) -N- ((3R,4S,5S) -1- ((S) -2- (1R,2R) -3- ((1S,2R) -1-hydroxy-1-phenylpropan-2-yl) amino) -1-methoxy-2-methyl-3-oxopropyl) p yrrolidin-1-yl) -3-methoxy-5-methyl-1-oxoheptan-4-yl) -N,3-dimethyl-2-((S) -3-methyl-2- (methylamino) butanamido) butanamide Iwọn Molecular: 717.98 Formula: C39H67N5O7 CAS: 474645-27-7 Solubility: DMSO titi di 20 mM Monomethyl Auristatin E jẹ itọsẹ dolastatin-10 peptide ti o ni agbara pẹlu iṣẹ antimitotic ti o lagbara ati iṣẹ-ṣiṣe antineoplastic ti o pọju gẹgẹbi apakan ti ẹya-ara ti antineoplastic.
