Super Lowest Price Protirelin - Linaclotide – JYMed

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Super Lowest Price Protirelin - Linaclotide – JYMed Detail:

Keywords

  • Linaclotide Base
  • most affordable price
  • CAS# 851199-59-2

Quick Details

  • ProName: Linaclotide
  • CasNo: 851199-59-2
  • Molecular Formula: C59H79N15O21S6
  • Appearance: white powder
  • Application: used for Curing constipation
  • DeliveryTime: prompt shipment
  • PackAge: according to customer’s requirements
  • Port: Shenzhen
  • ProductionCapacity: 1 Kilogram/Month
  • Purity: 98%
  • Storage: 2~8℃. protected from light
  • Transportation: by air
  • LimitNum: 1 Gram

Superiority

 

professional peptide manufacturer in china.
high quality with gmp grade
large scale with competitive price
our products include: generic bulk peptide apis, cosmetic peptide, custom peptides and veterinary peptides.

 

Details

 

Product:  Linaclotide
Synonym: Linaclotide Acetate
CAS No. : 851199-59-2
Molecular Formula: C59H79N15O21S6
Molecular Weight: 1526.8
Appearance: White powder
Purity: >98%
Sequence: NH2-Cys-Cys-Glu-Tyr-Cys-Cys-Asn-Pro-Ala-Cys-Thr-Gly-Cys-Tyr-OH

Linaclotide is a synthetic, fourteen amino acid peptide and agonist of intestinal guanylate cyclase type C (GC-C), which is structurally related to the guanylin peptide family, with secretagogue, analgesic and laxative activities. Upon oral administration, linaclotide binds to and activates GC-C receptors located on the luminal surface of the intestinal epithelium. This increases the concentration of intracellular cyclic guanosine monophosphate (cGMP), which is derived from guanosine triphosphate (GTP). cGMP activates the cystic fibrosis transmembrane conductance regulator (CFTR) and stimulates the secretion of chloride and bicarbonate into the intestinal lumen. This promotes sodium excretion into the lumen and results in increased intestinal fluid secretion. This ultimately accelerates GI transit of intestinal contents, improves bowel movement and relieves constipation. Increased extracellular cGMP levels may also exert an antinociceptive effect, through an as of yet not fully elucidated mechanism, that may involve modulation of nociceptors found on colonic afferent pain fibers. Linaclotide is minimally absorbed from the GI tract.

Company Profile:
company name:Shenzhen JYMed Technology Co.,Ltd.
Year Established:2009
Capital: 89.5 Million RMB
Main product: Oxytocin Acetate,Vasopressin Acetate,Desmopressin Acetate,Terlipressin acetate, Caspofungin acetate, Micafungin sodium, Eptifibatide acetate, Bivalirudin TFA, Deslorelin Acetate,Glucagon Acetate,Histrelin Acetate,Liraglutide Acetate,Linaclotide  Aceteate ,Degarelix Acetate,Buserelin Acetate,Cetrorelix Acetate,Goserelin
Acetate, Argireline Acetate, Metrixyl Acetate,Snap-8,…..
We strive for continuing innovations in new peptide synthesis technology and process optimization, and our technical team have over decade of experience in peptide synthesis.JYM has successfully submitted a lot
of ANDA peptide APIs and formulated products with CFDA and have more than fourty patents approved.
Our peptide plant is located in Nanjing, Jiangsu province and it has set up a facility of  30,000 square meters in compliance with cGMP guideline. The manufacture facility has been audited and inspected by both domestic and international clients.
With its excellent quality, most competitive price and strong technical support, JYM not only has gained recognitions for its products from Research organizations and Pharmaceutical industries, but also become one of the most reliable suppliers of peptides in China,. JYM is dedicated to be one of the world’s leading peptide provider in the near future.

Product detail pictures:

Super Lowest Price Protirelin -
 Linaclotide – JYMed detail pictures

Super Lowest Price Protirelin -
 Linaclotide – JYMed detail pictures


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  • It is not easy to find such a professional and responsible provider in today's time. Hope that we can maintain long-term cooperation.
    5 Stars By Gustave from Japan - 2016.10.13 10:47
    The sales manager is very patient, we communicated about three days before we decided to cooperate, finally, we are very satisfied with this cooperation!
    5 Stars By Eve from India - 2015.05.15 10:52

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