Palmitoyl Pentapeptide-3, also known as Matrixyl and Palmitoyl Pentapeptide-4, is a pentapeptide created by Sederma SA and Proctor & Gamble.

Palmitoyl Pentapeptide-3 stimulates the production of collagen, elastin, and glycosaminoglycans. It improves the appearance of fine lines and wrinkles and the skin’s moisturization levels, and, overtime, its firmness.

Palmitoyl Pentapeptide-3 is generally considered to be safe. However, according to Sederma, this ingredient should be used in concentrations ranging from 3% to 5% to work properly, and very few, if any, products on the market contain the recommended amount.

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