OEM Supply Thymalfasin - Linaclotide – JYMed
OEM Supply Thymalfasin - Linaclotide – JYMed Detail:
Keywords
- Linaclotide Base
- most affordable price
- CAS# 851199-59-2
Quick Details
- ProName: Linaclotide
- CasNo: 851199-59-2
- Molecular Formula: C59H79N15O21S6
- Appearance: white powder
- Application: used for Curing constipation
- DeliveryTime: prompt shipment
- PackAge: according to customer’s requirements
- Port: Shenzhen
- ProductionCapacity: 1 Kilogram/Month
- Purity: 98%
- Storage: 2~8℃. protected from light
- Transportation: by air
- LimitNum: 1 Gram
Superiority
Details
Product: Linaclotide
Synonym: Linaclotide Acetate
CAS No. : 851199-59-2
Molecular Formula: C59H79N15O21S6
Molecular Weight: 1526.8
Appearance: White powder
Purity: >98%
Sequence: NH2-Cys-Cys-Glu-Tyr-Cys-Cys-Asn-Pro-Ala-Cys-Thr-Gly-Cys-Tyr-OH
Linaclotide is a synthetic, fourteen amino acid peptide and agonist of intestinal guanylate cyclase type C (GC-C), which is structurally related to the guanylin peptide family, with secretagogue, analgesic and laxative activities. Upon oral administration, linaclotide binds to and activates GC-C receptors located on the luminal surface of the intestinal epithelium. This increases the concentration of intracellular cyclic guanosine monophosphate (cGMP), which is derived from guanosine triphosphate (GTP). cGMP activates the cystic fibrosis transmembrane conductance regulator (CFTR) and stimulates the secretion of chloride and bicarbonate into the intestinal lumen. This promotes sodium excretion into the lumen and results in increased intestinal fluid secretion. This ultimately accelerates GI transit of intestinal contents, improves bowel movement and relieves constipation. Increased extracellular cGMP levels may also exert an antinociceptive effect, through an as of yet not fully elucidated mechanism, that may involve modulation of nociceptors found on colonic afferent pain fibers. Linaclotide is minimally absorbed from the GI tract.
Product detail pictures:
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We keep on with the basic principle of "quality to start with, support very first, continuous improvement and innovation to meet the customers" for your management and "zero defect, zero complaints" as the quality objective. To great our service, we offer the items with all the superior top quality at the reasonable selling price for OEM Supply Thymalfasin - Linaclotide – JYMed, The product will supply to all over the world, such as: Romania, Cyprus, Puerto Rico, Now we have a excellent team supplying specialist service, prompt reply, timely delivery, excellent quality and best price to our customers. Satisfaction and good credit to every customer is our priority. We have been sincerely looking forward to cooperate with customers all over the world. We believe we can satisfy with you. We also warmly welcome customers to visit our company and purchase our solutions.
By Frank from Eindhoven - 2016.02.18 15:54
This company has the idea of "better quality, lower processing costs, prices are more reasonable", so they have competitive product quality and price, that's the main reason we chose to cooperate.
By David from Pakistan - 2015.05.22 12:13
