OEM Supply Thymalfasin - Linaclotide – JYMed

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OEM Supply Thymalfasin - Linaclotide – JYMed Detail:

Keywords

  • Linaclotide Base
  • most affordable price
  • CAS# 851199-59-2

Quick Details

  • ProName: Linaclotide
  • CasNo: 851199-59-2
  • Molecular Formula: C59H79N15O21S6
  • Appearance: white powder
  • Application: used for Curing constipation
  • DeliveryTime: prompt shipment
  • PackAge: according to customer’s requirements
  • Port: Shenzhen
  • ProductionCapacity: 1 Kilogram/Month
  • Purity: 98%
  • Storage: 2~8℃. protected from light
  • Transportation: by air
  • LimitNum: 1 Gram

Superiority

 

professional peptide manufacturer in china.
high quality with gmp grade
large scale with competitive price
our products include: generic bulk peptide apis, cosmetic peptide, custom peptides and veterinary peptides.

 

Details

 

Product:  Linaclotide
Synonym: Linaclotide Acetate
CAS No. : 851199-59-2
Molecular Formula: C59H79N15O21S6
Molecular Weight: 1526.8
Appearance: White powder
Purity: >98%
Sequence: NH2-Cys-Cys-Glu-Tyr-Cys-Cys-Asn-Pro-Ala-Cys-Thr-Gly-Cys-Tyr-OH

Linaclotide is a synthetic, fourteen amino acid peptide and agonist of intestinal guanylate cyclase type C (GC-C), which is structurally related to the guanylin peptide family, with secretagogue, analgesic and laxative activities. Upon oral administration, linaclotide binds to and activates GC-C receptors located on the luminal surface of the intestinal epithelium. This increases the concentration of intracellular cyclic guanosine monophosphate (cGMP), which is derived from guanosine triphosphate (GTP). cGMP activates the cystic fibrosis transmembrane conductance regulator (CFTR) and stimulates the secretion of chloride and bicarbonate into the intestinal lumen. This promotes sodium excretion into the lumen and results in increased intestinal fluid secretion. This ultimately accelerates GI transit of intestinal contents, improves bowel movement and relieves constipation. Increased extracellular cGMP levels may also exert an antinociceptive effect, through an as of yet not fully elucidated mechanism, that may involve modulation of nociceptors found on colonic afferent pain fibers. Linaclotide is minimally absorbed from the GI tract.

Company Profile:
company name:Shenzhen JYMed Technology Co.,Ltd.
Year Established:2009
Capital: 89.5 Million RMB
Main product: Oxytocin Acetate,Vasopressin Acetate,Desmopressin Acetate,Terlipressin acetate, Caspofungin acetate, Micafungin sodium, Eptifibatide acetate, Bivalirudin TFA, Deslorelin Acetate,Glucagon Acetate,Histrelin Acetate,Liraglutide Acetate,Linaclotide  Aceteate ,Degarelix Acetate,Buserelin Acetate,Cetrorelix Acetate,Goserelin
Acetate, Argireline Acetate, Metrixyl Acetate,Snap-8,…..
We strive for continuing innovations in new peptide synthesis technology and process optimization, and our technical team have over decade of experience in peptide synthesis.JYM has successfully submitted a lot
of ANDA peptide APIs and formulated products with CFDA and have more than fourty patents approved.
Our peptide plant is located in Nanjing, Jiangsu province and it has set up a facility of  30,000 square meters in compliance with cGMP guideline. The manufacture facility has been audited and inspected by both domestic and international clients.
With its excellent quality, most competitive price and strong technical support, JYM not only has gained recognitions for its products from Research organizations and Pharmaceutical industries, but also become one of the most reliable suppliers of peptides in China,. JYM is dedicated to be one of the world’s leading peptide provider in the near future.

Product detail pictures:

OEM Supply Thymalfasin -
 Linaclotide – JYMed detail pictures

OEM Supply Thymalfasin -
 Linaclotide – JYMed detail pictures


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Persisting in "High good quality, Prompt Delivery, Aggressive Price", we've established long-term cooperation with shoppers from each overseas and domestically and get new and previous clients' high comments for OEM Supply Thymalfasin - Linaclotide – JYMed, The product will supply to all over the world, such as: Paris , Armenia , Haiti , Our company considers that selling is not only to gain profit but also popularize the culture of our company to the world. So we are working hard to give you the wholehearted service and willing to give you the most competitive price in the market
  • Managers are visionary, they have the idea of "mutual benefits, continuous improvement and innovation", we have a pleasant conversation and Cooperation.
    5 Stars By Dora from Georgia - 2015.06.19 10:42
    The factory has advanced equipment, experienced staffs and good management level, so product quality had assurance, this cooperation is very relaxed and happy!
    5 Stars By Anne from Netherlands - 2016.10.25 15:53

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