Hot sale Factory Alarelin Acetate Supplier - Linaclotide – JYMed
Hot sale Factory Alarelin Acetate Supplier - Linaclotide – JYMed Detail:
Keywords
- Linaclotide Base
- most affordable price
- CAS# 851199-59-2
Quick Details
- ProName: Linaclotide
- CasNo: 851199-59-2
- Molecular Formula: C59H79N15O21S6
- Appearance: white powder
- Application: used for Curing constipation
- DeliveryTime: prompt shipment
- PackAge: according to customer’s requirements
- Port: Shenzhen
- ProductionCapacity: 1 Kilogram/Month
- Purity: 98%
- Storage: 2~8℃. protected from light
- Transportation: by air
- LimitNum: 1 Gram
Superiority
Details
Product: Linaclotide
Synonym: Linaclotide Acetate
CAS No. : 851199-59-2
Molecular Formula: C59H79N15O21S6
Molecular Weight: 1526.8
Appearance: White powder
Purity: >98%
Sequence: NH2-Cys-Cys-Glu-Tyr-Cys-Cys-Asn-Pro-Ala-Cys-Thr-Gly-Cys-Tyr-OH
Linaclotide is a synthetic, fourteen amino acid peptide and agonist of intestinal guanylate cyclase type C (GC-C), which is structurally related to the guanylin peptide family, with secretagogue, analgesic and laxative activities. Upon oral administration, linaclotide binds to and activates GC-C receptors located on the luminal surface of the intestinal epithelium. This increases the concentration of intracellular cyclic guanosine monophosphate (cGMP), which is derived from guanosine triphosphate (GTP). cGMP activates the cystic fibrosis transmembrane conductance regulator (CFTR) and stimulates the secretion of chloride and bicarbonate into the intestinal lumen. This promotes sodium excretion into the lumen and results in increased intestinal fluid secretion. This ultimately accelerates GI transit of intestinal contents, improves bowel movement and relieves constipation. Increased extracellular cGMP levels may also exert an antinociceptive effect, through an as of yet not fully elucidated mechanism, that may involve modulation of nociceptors found on colonic afferent pain fibers. Linaclotide is minimally absorbed from the GI tract.
Product detail pictures:
Related Product Guide:
Bachem | Terlipressin Acetate Gmp Manufacturer
Atrial Natriuretic Peptide Frameshift Mutation in Familial Atrial Fibrillation | Lanreotide
Persisting in "High quality, Prompt Delivery, Aggressive Price", we have established long-term cooperation with clientele from both equally overseas and domestically and get new and old clients' higher comments for Hot sale Factory Alarelin Acetate Supplier - Linaclotide – JYMed, The product will supply to all over the world, such as: New Orleans, Serbia, Netherlands, To have much more enterprise. ompanions, we've got updated the item list and seek for optimistic co-operation. Our web-site shows the latest and complete information and facts about our merchandise list and company. For further acknowledge, our consultant service group in Bulgaria will reply to all of the inquiries and complications immediately. They're about to make their finest effort to meet buyers need. Also we support the delivery of absolutely free samples. Business visits to our business in Bulgaria and factory are generally welcome for a win-win negotiation. Hope to expertise a happy company co-operation perform with you.
By Miguel from Burundi - 2016.09.28 18:29
Timely delivery, strict implementation of the contract provisions of the goods, encountered special circumstances, but also actively cooperate, a trustworthy company!
By Jerry from Slovenia - 2016.02.28 14:19