Hot sale Factory Alarelin Acetate Supplier - Linaclotide – JYMed
Hot sale Factory Alarelin Acetate Supplier - Linaclotide – JYMed Detail:
Keywords
- Linaclotide Base
- most affordable price
- CAS# 851199-59-2
Quick Details
- ProName: Linaclotide
- CasNo: 851199-59-2
- Molecular Formula: C59H79N15O21S6
- Appearance: white powder
- Application: used for Curing constipation
- DeliveryTime: prompt shipment
- PackAge: according to customer’s requirements
- Port: Shenzhen
- ProductionCapacity: 1 Kilogram/Month
- Purity: 98%
- Storage: 2~8℃. protected from light
- Transportation: by air
- LimitNum: 1 Gram
Superiority
Details
Product: Linaclotide
Synonym: Linaclotide Acetate
CAS No. : 851199-59-2
Molecular Formula: C59H79N15O21S6
Molecular Weight: 1526.8
Appearance: White powder
Purity: >98%
Sequence: NH2-Cys-Cys-Glu-Tyr-Cys-Cys-Asn-Pro-Ala-Cys-Thr-Gly-Cys-Tyr-OH
Linaclotide is a synthetic, fourteen amino acid peptide and agonist of intestinal guanylate cyclase type C (GC-C), which is structurally related to the guanylin peptide family, with secretagogue, analgesic and laxative activities. Upon oral administration, linaclotide binds to and activates GC-C receptors located on the luminal surface of the intestinal epithelium. This increases the concentration of intracellular cyclic guanosine monophosphate (cGMP), which is derived from guanosine triphosphate (GTP). cGMP activates the cystic fibrosis transmembrane conductance regulator (CFTR) and stimulates the secretion of chloride and bicarbonate into the intestinal lumen. This promotes sodium excretion into the lumen and results in increased intestinal fluid secretion. This ultimately accelerates GI transit of intestinal contents, improves bowel movement and relieves constipation. Increased extracellular cGMP levels may also exert an antinociceptive effect, through an as of yet not fully elucidated mechanism, that may involve modulation of nociceptors found on colonic afferent pain fibers. Linaclotide is minimally absorbed from the GI tract.
Product detail pictures:
Related Product Guide:
Sartan Recalls Beg the Question: Is Compendial Impurity Testing Enough? | Pramlintide Acetate Gmp Exporter
Upregulation of BMSCs Osteogenesis by Positively-Charged Tertiary Amines on Polymeric Implants via Charge/iNOS Signaling Pathway | Trelstar(Triptorelin Pamoate)
Attaining consumer satisfaction is our company's purpose without end. We will make wonderful endeavours to produce new and top-quality merchandise, satisfy your exclusive requirements and supply you with pre-sale, on-sale and after-sale services for Hot sale Factory Alarelin Acetate Supplier - Linaclotide – JYMed , The product will supply to all over the world, such as: Florida, Oman, Japan, They are sturdy modeling and promoting effectively all over the world. Never ever disappearing major functions within a quick time, it's a have to in your case of fantastic good quality. Guided by the principle of "Prudence, Efficiency, Union and Innovation. the corporation. ake an excellent efforts to expand its international trade, raise its organization. rofit and raise its export scale. We have been confident that we've been going to have a bright prospect and to be distributed all over the world in the years to come.
By Nora from Sheffield - 2015.12.10 19:03
It is a very good, very rare business partners, looking forward to the next more perfect cooperation!
By Victor from Australia - 2015.12.11 11:26
