factory Outlets for Synthetic Goserelin Gmp Supplier From China - Linaclotide – JYMed
factory Outlets for Synthetic Goserelin Gmp Supplier From China - Linaclotide – JYMed Detail:
Keywords
- Linaclotide Base
- most affordable price
- CAS# 851199-59-2
Quick Details
- ProName: Linaclotide
- CasNo: 851199-59-2
- Molecular Formula: C59H79N15O21S6
- Appearance: white powder
- Application: used for Curing constipation
- DeliveryTime: prompt shipment
- PackAge: according to customer’s requirements
- Port: Shenzhen
- ProductionCapacity: 1 Kilogram/Month
- Purity: 98%
- Storage: 2~8℃. protected from light
- Transportation: by air
- LimitNum: 1 Gram
Superiority
Details
Product: Linaclotide
Synonym: Linaclotide Acetate
CAS No. : 851199-59-2
Molecular Formula: C59H79N15O21S6
Molecular Weight: 1526.8
Appearance: White powder
Purity: >98%
Sequence: NH2-Cys-Cys-Glu-Tyr-Cys-Cys-Asn-Pro-Ala-Cys-Thr-Gly-Cys-Tyr-OH
Linaclotide is a synthetic, fourteen amino acid peptide and agonist of intestinal guanylate cyclase type C (GC-C), which is structurally related to the guanylin peptide family, with secretagogue, analgesic and laxative activities. Upon oral administration, linaclotide binds to and activates GC-C receptors located on the luminal surface of the intestinal epithelium. This increases the concentration of intracellular cyclic guanosine monophosphate (cGMP), which is derived from guanosine triphosphate (GTP). cGMP activates the cystic fibrosis transmembrane conductance regulator (CFTR) and stimulates the secretion of chloride and bicarbonate into the intestinal lumen. This promotes sodium excretion into the lumen and results in increased intestinal fluid secretion. This ultimately accelerates GI transit of intestinal contents, improves bowel movement and relieves constipation. Increased extracellular cGMP levels may also exert an antinociceptive effect, through an as of yet not fully elucidated mechanism, that may involve modulation of nociceptors found on colonic afferent pain fibers. Linaclotide is minimally absorbed from the GI tract.
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We insist on the principle of development of 'High quality, Efficiency, Sincerity and Down-to-earth working approach' to provide you with excellent service of processing for factory Outlets for Synthetic Goserelin Gmp Supplier From China - Linaclotide – JYMed, The product will supply to all over the world, such as: South Africa, Puerto Rico, Albania, Our stock have valued 8 million dollar , you can find the competitive parts within short delivery time. Our company is not only your partner in business, but also our company is your assistant in the coming corporation.
By Laura from Ecuador - 2015.02.04 14:13
The factory technical staff gave us a lot of good advice in the cooperation process, this is very good, we are very grateful.
By Mamie from Hungary - 2015.11.04 10:32
