100% Original Liraglutide - Linaclotide – JYMed

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100% Original Liraglutide - Linaclotide – JYMed Detail:

Keywords

Linaclotide Base
most affordable price
CAS# 851199-59-2

Quick Details

ProName: Linaclotide
CasNo: 851199-59-2
Molecular Formula: C59H79N15O21S6
Appearance: white powder
Application: used for Curing constipation
DeliveryTime: prompt shipment
PackAge: according to customer’s requirements
Port: Shenzhen
ProductionCapacity: 1 Kilogram/Month
Purity: 98%
Storage: 2~8℃. protected from light
Transportation: by air
LimitNum: 1 Gram

Superiority

professional peptide manufacturer in china.

high quality with gmp grade

large scale with competitive price

our products include: generic bulk peptide apis, cosmetic peptide, custom peptides and veterinary peptides.

Details

Product: Linaclotide
Synonym: Linaclotide Acetate
CAS No. : 851199-59-2
Molecular Formula: C59H79N15O21S6
Molecular Weight: 1526.8
Appearance: White powder
Purity: >98%
Sequence: NH2-Cys-Cys-Glu-Tyr-Cys-Cys-Asn-Pro-Ala-Cys-Thr-Gly-Cys-Tyr-OH

Linaclotide is a synthetic, fourteen amino acid peptide and agonist of intestinal guanylate cyclase type C (GC-C), which is structurally related to the guanylin peptide family, with secretagogue, analgesic and laxative activities. Upon oral administration, linaclotide binds to and activates GC-C receptors located on the luminal surface of the intestinal epithelium. This increases the concentration of intracellular cyclic guanosine monophosphate (cGMP), which is derived from guanosine triphosphate (GTP). cGMP activates the cystic fibrosis transmembrane conductance regulator (CFTR) and stimulates the secretion of chloride and bicarbonate into the intestinal lumen. This promotes sodium excretion into the lumen and results in increased intestinal fluid secretion. This ultimately accelerates GI transit of intestinal contents, improves bowel movement and relieves constipation. Increased extracellular cGMP levels may also exert an antinociceptive effect, through an as of yet not fully elucidated mechanism, that may involve modulation of nociceptors found on colonic afferent pain fibers. Linaclotide is minimally absorbed from the GI tract.

Company Profile:

company name:Shenzhen JYMed Technology Co.,Ltd.

Year Established:2009

Capital: 89.5 Million RMB

Main product: Oxytocin Acetate,Vasopressin Acetate,Desmopressin Acetate,Terlipressin acetate, Caspofungin acetate, Micafungin sodium, Eptifibatide acetate, Bivalirudin TFA, Deslorelin Acetate,Glucagon Acetate,Histrelin Acetate,Liraglutide Acetate,Linaclotide Aceteate ,Degarelix Acetate,Buserelin Acetate,Cetrorelix Acetate,Goserelin

Acetate, Argireline Acetate, Metrixyl Acetate,Snap-8,…..

We strive for continuing innovations in new peptide synthesis technology and process optimization, and our technical team have over decade of experience in peptide synthesis.JYM has successfully submitted a lot

of ANDA peptide APIs and formulated products with CFDA and have more than fourty patents approved.

Our peptide plant is located in Nanjing, Jiangsu province and it has set up a facility of 30,000 square meters in compliance with cGMP guideline. The manufacture facility has been audited and inspected by both domestic and international clients.

With its excellent quality, most competitive price and strong technical support, JYM not only has gained recognitions for its products from Research organizations and Pharmaceutical industries, but also become one of the most reliable suppliers of peptides in China,. JYM is dedicated to be one of the world’s leading peptide provider in the near future.

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Assume full responsibility to satisfy all needs of our clients; achieve continual advancements by endorsing the expansion of our purchasers; turn into the final permanent cooperative partner of clientele and maximize the interests of clients for 100% Original Liraglutide - Linaclotide – JYMed, The product will supply to all over the world, such as: Bahamas, European, Turkmenistan, we rely on own advantages to build a mutual-benefit commerce mechanism with our cooperative partners. As a result, we've gained a global sales network reaching the Middle East, Turkey, Malaysia and Vietnamese.

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