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Monomethylauristatin F (MMAF)
Navê Kîmyayî: (S)-2-((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-N,3-dimethyl-2-((S)-3-methyl-2-(methylamino)butanamido)butanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanamido)-3-phenylpropanoic acid Giraniya Molekulî: 731.96 Formul: C39H65N5O8 CAS#: 141205-32-5 Çareserbûn: DMSO heta 20 mM Çalakiya Biyolojîkî Monomethyl auristatin F (MMAF) an desmethyl-auristatin F ajanek dij-tubulin e ku dabeşbûna hucreyê bi astengkirina polîmerîzasyona tubulinê asteng dike. Ew ... -
Monomethyl Auristatin E (MMAE)
Navê Kîmyayî: (S)-N-((3R,4S,5S)-1-((S)-2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidin-1-yl)-3-methoxy-5-methyl-1-oxoheptan-4-yl)-N,3-dimethyl-2-((S)-3-methyl-2-(methylamino)butanamido)butanamide Giraniya Molekulî: 717.98 Formula: C39H67N5O7 CAS: 474645-27-7 Çareserbûn: DMSO heta 20 mM Monomethyl Auristatin E derivatîfek peptîd a dolastatin-10 e ku xwedî çalakiya antîmîtotîk a bihêz û çalakiya antîneoplastîk a potansiyel wekî beşek ji antîkorek...
