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Monomethylauristatin F (MMAF)
Ainm Ceimigeach: (S)-2-((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-N,3-dimethyl-2-((S)-3-methyl-2-(methylamino)butanamido)butanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanamido)-3-phenylpropanoic acid Cuideam Moileciuil: 731.96 Foirmle: C39H65N5O8 CAS#: 141205-32-5 So-sgaoilteachd: DMSO suas ri 20 mM Gnìomhachd Bhith-eòlasach Tha monomethyl auristatin F (MMAF) no desmethyl-auristatin F na àidseant an-aghaidh tubulin a chuireas casg air roinneadh cealla le bhith a’ cur bacadh air poileimearachadh tubulin. Tha e na ... -
Monomethyl Auristatin E (MMAE)
Ainm Ceimigeach: (S)-N-((3R,4S,5S)-1-((S)-2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidin-1-yl)-3-methoxy-5-methyl-1-oxoheptan-4-yl)-N,3-dimethyl-2-((S)-3-methyl-2-(methylamino)butanamido)butanamide Cuideam Moileciuil: 717.98 Foirmle: C39H67N5O7 CAS: 474645-27-7 So-sgaoilteachd: DMSO suas ri 20 mM Tha Monomethyl Auristatin E na thoradh peptide dolastatin-10 le gnìomhachd antimitotach làidir agus gnìomhachd antineoplastic comasach mar phàirt de antibody...
