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Monometylauristatine F (MMAF)
Gemyske namme: (S)-2-((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-N,3-dimethyl-2-((S)-3-methyl-2-(methylamino)butanamido)butanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanamido)-3-phenylpropanoic acid Molekulêr gewicht: 731.96 Formule: C39H65N5O8 CAS#: 141205-32-5 Oplosberens: DMSO oant 20 mM Biologyske aktiviteit Monomethyl auristatin F (MMAF) of desmethyl-auristatin F is in anty-tubuline-agint dat seldieling remt troch de polymerisaasje fan tubuline te blokkearjen. It is in ... -
Monomethyl Auristatin E (MMAE)
Gemyske namme: (S)-N-((3R,4S,5S)-1-((S)-2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidin-1-yl)-3-methoxy-5-methyl-1-oxoheptan-4-yl)-N,3-dimethyl-2-((S)-3-methyl-2-(methylamino)butanamido)butanamide Molekulêr gewicht: 717.98 Formule: C39H67N5O7 CAS: 474645-27-7 Oplosberens: DMSO oant 20 mM Monomethyl Auristatin E is in dolastatin-10 peptidederivaat mei krêftige antimitoatyske aktiviteit en potinsjele antineoplastyske aktiviteit as ûnderdiel fan in antistof...
