[Lipeptide tsa Linear]
Mekhoa ea ho Kopanya: SPPS, LPPS, L/SPPS, MPSPPS, HPPS
Phihlelo: Tatelano ea Peptide ho tloha ho 2 ho isa ho 80 amino acid; li-peptide tse fetang 20,000 tse melang li isoa ho bareki
Sekhahla sa Tlhahiso: Ho tloha ho milligram ho ea ho sekala sa makholo a mangata-kilogram
Khetho ea Boleng: E sa hloekang, ≥90%, ≥95%, ≥98%, ≥99% bohloeki, e etselitsoe ho fihlela litlhoko tse fapaneng tsa boleng
Nako ea Ketapele: Bakeng sa li-peptide tse ka tlase ho 30 amino acid (mg scale), ho beleha ka potlako joaloka libeke tse 2-3
[Lipeptide tsa Baesekele]
Maano a Cyclization: Litlamo tsa Disulfide (1-3 pair), li-bond tsa thioether, li-amide bond, li-ester bond, k'hemistri ea tobetsa, li-olefin bonds
Libaka tsa Libaesekele: Hlooho-ho-mohatla, ketane ea mahlakoreng, C-terminal-to-side-chain, N-terminal-to-side-chain
Phihlelo: Tatelano ho tloha ho 4 ho ea ho 80 amino acid; ho feta 5,000 cyclic peptide e rometsoe ka katleho
Sekhahla sa Tlhahiso: Ho tloha ho milligram ho ea ho sekala sa makholo a mangata-kilogram
Khetho ea Boleng: E sa hloekang, ≥90%, ≥95%, ≥98%, ≥99% bohloeki
Nako ea ho Tsamaisa: Bakeng sa li-peptide tsa monocyclic tlas'a 30 amino acid (mg scale), ho beleha ka potlako joaloka libeke tsa 2-3
[Lipeptide tse Fetotsoeng]
Mefuta ea Liphetoho: Acetylation, alkylation, liphetoho tsa ketane e telele, isotope labeling, fluorescent le dae labeling, glycosylation, phosphorylation, esterification, liphetoho tse khethehileng tsa sebopeho, PEGylation, le tse ling.
Libaka tsa Liphetoho: N-terminal, C-terminal, liketane tse ka thōko
Phihlelo: Tatelano ho tloha ho 2 ho ea ho 80 amino acid; li-peptide tse fetotsoeng tse fetang 5,000 li rometsoe ka katleho
Sekhahla sa Tlhahiso: Ho tloha ho milligram ho ea ho sekala sa makholo a mangata-kilogram
Khetho ea Boleng: E sa hloekang, ≥90%, ≥95%, ≥98%, ≥99% bohloeki
Nako ea ho Tsamaisa: Bakeng sa li-peptide tse fetotsoeng tlas'a 30 amino acid (mg scale), ho tsamaisoa ka potlako joaloka libeke tsa 2-3
[Neoantigen Peptides]
Sebaka sa Ts'ebeletso: Tlhahlobo ea tatellano, nts'etsopele ea ts'ebetso, lipatlisiso tsa boleng, tšehetso ea ho kenya IND, tlhahiso ea GMP
Phihlelo: Tatelano ho tloha ho 5 ho ea ho 30 amino acid; li-peptide tse fetang 100 tsa neoantigen li rometsoe ka katleho
Sekhahla sa Tlhahiso: Ho tloha ho milligram ho ea ho gram scale
Likhetho tsa Boleng: ≥95%, ≥98%, ≥99% bohloeki
Nako ea Pele: Bakeng sa li-peptide tsa neoantigen tlas'a 30 amino acid (mg scale), ho beleha ka potlako joaloka libeke tsa 2-3
[Peptide Conjugates]
Mefuta ea Conjugation: PDCs, RDCs, peptide-drug conjugates, peptide-natural compound conjugates, le tse ling.
Boiphihlelo: Likhokahano tse fetang 100 tsa peptide li rometsoe ka katleho
Sekala sa Tlhahiso: Ho tloha ho milligram ho ea ho kilogramme scale
Likhetho tsa Boleng: ≥95%, ≥98%, ≥99% bohloeki
Nako ea ho Tsamaisa: Bakeng sa li-conjugates tsa peptide tlas'a 30 amino acids (mg scale), ho tsamaisoa ka potlako joaloka libeke tsa 2-3
[Li-peptide tse ling]
Sebaka sa Tšebeletso: Li-peptide tsa makala, li-peptide tse ipokellang, li-peptide tse phunyeletsang liseleng, li-peptide tsa semi-synthetic, joalo-joalo.
Phihlelo: Tatelano ho tloha 5 ho 88 amino acid; li-peptide tse fetang 1,000 tse ikhethang li rometsoe ka katleho
Sekala sa Tlhahiso: Ho tloha ho milligram ho ea ho kilogramme scale
Khetho ea Boleng: E sa hloekang, ≥90%, ≥95%, ≥98%, ≥99% bohloeki
Nako ea ho Tsamaisa: Bakeng sa li-peptide tse khethehileng tlas'a 30 amino acid (mg scale), ho tsamaisoa ka potlako joaloka libeke tsa 2-3
